Monje A, Pons R, Vilarrasa J, Nart J, Wang H-L. Journal of Periodontology 2023;94(3):323–335. doi:10.1002/JPER.22-0511
Summary prepared by 
— not the original paper
Why we present this paper
This page is published by HANS KOREA CO.,Ltd., the manufacturer of the NiTi Brush1. We share selected peer-reviewed studies so that clinicians who use the NiTi Brush can see how it was used in published clinical protocols, with the ultimate aim of better outcomes for patients.
Independence
The study was designed, conducted and published independently by its authors. The authors and the publisher are not associated with this page and do not endorse HANS Korea or its products. According to the paper, the study was self-funded, and the allografts and barrier membranes were donated by LifeNet Health and Osteogenics. According to the paper’s conflict-of-interest statement, the authors have no direct financial interests with the products and instruments listed in the paper.
About this study
This paper investigates whether adding a resorbable cross-linked collagen barrier membrane to grafting with a mixture of mineralized and demineralized allografts changes the outcome of reconstructive surgery for peri-implantitis with contained defects. As part of the surgical protocol described by the authors, NiTi brushes were used together with curettes for debridement of granulation tissue, and for surface decontamination.
How the NiTi Brush was used in this study
As reported by the authors.
| Item | As reported in the paper |
|---|---|
| Instrument | NiTi Brush (HANS Korea), named in the paper as “NiTi brushes” with the manufacturer given as Hans Korea Co., Gyeonggi-do, Korea |
| Step in the protocol | Debridement of granulation tissue, together with curettes; then, after implantoplasty where uncontained defect components were present, surface decontamination (the authors’ terms) |
| Speed | 600 rpm (surface decontamination) |
| Brushing time | About 2–3 minutes (surface decontamination) |
| Irrigation | The paper does not state whether irrigation was used while brushing; brushing was followed by hydrogen peroxide (3%) for 2 minutes and irrigation with saline |
The study at a glance
Two-arm randomized clinical trial (NCT05282667): 33 patients with 48 implants with peri-implantitis and contained defects completed the study; the defects were grafted with the allograft mixture with or without the membrane, and patients were followed for 12 months. The authors conclude that reconstructive therapy with the allograft mixture is effective in clinically resolving peri-implantitis and in gaining radiographic marginal bone level, and that adding a barrier membrane does not seem to enhance the outcomes of contained bone defects.
A secondary analysis of the same trial (defect angle) is summarized separately: Monje et al. 2023, Clinical Implant Dentistry and Related Research, doi:10.1111/cid.13244 (our summary).
Please read the original paper
For the methods, results and limitations, see the original article (open access): https://doi.org/10.1002/jper.22-0511
Reported study conditions are the authors’ and may differ from the Instructions for Use. Use the NiTi Brush only as described in the IFU (implant motor, 600–1,200 rpm, external saline irrigation, single use).
Source: Monje A, Pons R, Vilarrasa J, Nart J, Wang H-L. J Periodontol 2023;94(3):323–335, © 2022 The Authors, published by Wiley Periodicals LLC on behalf of the American Academy of Periodontology, open access under the Creative Commons Attribution License (CC BY). Summary and table by HANS Korea; wording adapted.
Contact and removal. If you are an author of this paper or its publisher and would prefer this page not to appear, or if you believe it affects your rights or reputation in any way, please write to [email protected]. At the request of the authors or the publisher, we will remove the page promptly. Any other concern will be reviewed promptly and the page corrected or removed where appropriate.
1 The NiTi Brush is a rotary brush with nickel-titanium alloy bristles, developed by HANS Korea since 2010. Rotary brushes of this kind are generically called “titanium brushes” (see What is a titanium brush); the official product name is NiTi Brush for Peri-implantitis. ↩